Sclerotherapy is a procedure used by doctors to treat spider veins. The doctor uses a very fine needle to inject a solution into the problem veins, causing them to swell, stick together, scar, and eventually fade from view. Generally, 50 percent to 80 percent of injected veins disappear with each session; it takes 3 to 6 weeks for spider veins to disappear, with larger veins disappearing in about 3 to 4 months.