What is Lupus?

Lupus is a complex autoimmune disorder where the body’s cells are attacked by one’s own immune system. This leads to inflammation and damage to various body tissues. Lupus can affect many parts of the body including the joints, kidneys, skin, heart, lungs, blood vessels, and brain. The organs that are affected are different for every person.

There are several types of lupus

  1. Systemic Lupus Erythematosus (SLE): lupus that affects multiple tissues and organs
  2. Cutaneous (skin) lupus including Discoid Lupus Erythematosus (DLE) and subacute cutaneous lupus
  3. Lupus kidney disease also known as Lupus Nephritis

At present, there is no cure for lupus. However, it can be effectively managed and most people with lupus can lead an active and healthy life.

The Lupus Clinic at Boston Medical Center

The Lupus Clinic at Boston Medical Center is a partnership between the Departments of Rheumatology, Dermatology, Nephrology, and Obstetrics/Gynecology. Our specialists in these departments have experience caring for hundreds of patients with chronic autoimmune diseases, including lupus.  In the Lupus Clinic, patients can be seen by multiple physicians on the same day for convenient and comprehensive care.  In addition, many of our physicians conduct research to better understand the development and treatment of lupus. This includes clinical trials and an autoimmune disease patient registry. 

We have a monthly lupus meeting where researchers, physicians, and patient care providers meet to discuss research breakthroughs, new therapies, and how to improve the patient experience.

BMC’s lupus patient population is diverse. We strive to provide exceptional care to all patients - without exception.

Referring Providers

Please contact the patient navigator, Supraja Narasimhan at 617.638.1831 to refer a patient.
Referrals can also be faxed to 617.638.7454. On the cover letter, please specify “Lupus Clinic at BMC” and “Attention: Supraja Narasimhan.”

Contact Us

Our Team

Renal Medicine Doctors

Ramon G Bonegio, MD

Nephrologist

Special Interests

Lupus nephritis, Systemic lupus erythematosus (SLE), Autoimmune kidney disease, Vasculitis, Chronic kidney disease

Hanna Menn-Josephy, MD

Instructor of Medicine, Boston University School of Medicine, Boston Massachusetts

Special Interests

Autoimmune kidney disease, Lupus nephritis

Ian R Rifkin, MB, BCh

Assistant Professor of Medicine, Boston University School of Medicine, Boston MA

Special Interests

Lupus nephritis

Placeholder image for doctor

David J Salant, MD

Chief, Section of Nephrology
Professor of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston MA

Special Interests

Kidney disease, Glomerulonephritis, Proteinuria, Lupus, Kidney stones

Rheumatologists

Eugene Y Kissin, MD

Clinical Professor of Medicine, Boston University School of Medicine

Special Interests

Rheumatoid Arthritis, Psoriatic Arthritis, Tendonitis/Bursitis, Seronegative arthritis, Myositis

Michael R York, MD

Assistant Professor of Medicine, Boston University School of Medicine, Boston MA
Rheumatologist

Special Interests

Scleroderma, Systemic sclerosis, Morphea, Lupus, Psoriatic arthritis

Dermatologists

Christina Lam, MD

Assistant Professor of Dermatology, Boston University School of Medicine, Boston MA

Special Interests

Lupus, Dermatomyositis, Scleroderma, Morphea, Vasculitis

Obstetricians and Gynecologists

Christina D Yarrington, MD, FACOG

Assistant Professor of Obstetrics & Gynecology, Boston University School of Medicine

Special Interests

Diabetes in pregnancy, Autoimmune disease in pregnancy, Lupus in pregnancy, Obesity medicine

Carlos Sian
Clinical Trial Manager
Phone: 617.638.5965

Supraja Narasimhan, PhD
Project Manager/Patient Navigator
Phone: 617.638.1831

Patient Resources

Patient Information

Lupus Foundation of New England: A local organization that hosts lupus educational events, fundraisers, and other activities.

Research Overview

Lupus Clinical Research

Our physician scientists work with a talented group of researchers to investigate the causes of immune system disorders. We collaborate with pharmaceutical companies in the Boston area to develop new treatments for lupus and other autoimmune diseases.

Our patients are vital partners in this research. We are currently enrolling patients with all forms of lupus, patients with autoimmune diseases other than lupus, and patients with chronic kidney disease in an Autoimmune Disease Registry and Repository. The goal of the registry and repository is to use patient samples collected for research purposes to advance our understanding of how the immune system attacks healthy cells and causes organ injury and to identify new targets for therapy.

We are also enrolling patients in research studies that involve a single blood donation to compare immune cell function between diseased individuals and healthy volunteers and to investigate how variations in genes (inherited from your parents) may contribute to the development of lupus.

If you are interested in participating in one of our research studies, please contact Carlos Sian at 617.638.5965.

To learn more about lupus research at Boston Medical Center, please visit our team members’ profiles.

Clinical Trials

Many of lupus patients, despite receiving the standard-of-care treatment for lupus or lupus nephritis, still do not achieve a complete remission. Some patients cannot tolerate the standard-of-care treatments because they develop significant side effects.

We offer patients the opportunity to participate in clinical trials and receive investigational treatments for lupus. Investigational treatments are medications that are not currently approved by the Food and Drug Administration to treat lupus. To learn more about what a clinical trial is, visit clinicaltrials.gov and select “About Clinical Studies.”

We are currently enrolling patients in the following clinical trials:

I. Sponsor: Genentech

Study Drug: GDC-0853, a Btk inhibitor

Patient population: Systemic lupus erythematosus (SLE)

Title of study: A Phase II, randomized, double-blind, placebo-controlled study of the safety and efficacy of GDC-0853 in patients with moderate to severe active systemic lupus erythematosus

For more information about the outcome measures of the study and eligibility criteria, visit clinicaltrials.gov and type in the identifier NCT02908100

If you are interested in participating in one of our research studies, please contact Carlos Sian at 617.638.5965.

Residency and Fellowship Information

Rheumatology Education

Boston Medical Center is affiliated with the Boston University School of Medicine (BUSM).

To learn about our academic and fellowship programs in rheumatology, please visit:
http://www.bumc.bu.edu/rheumatology/fellowship/

To learn about our academic and fellowship programs in nephrology, please visit:
https://www.bumc.bu.edu/nephrology/fellowship/