What is Esophageal Cancer?

Esophageal cancer is the uncontrolled growth of abnormal cells in the esophagus, which is a flexible tube connecting the throat to the stomach. Generally between 10 and 13 inches long, the esophagus contracts when one swallows, to push food down into the stomach. Mucus helps move this process along.

Ninety percent of esophageal cancers are one of two types: squamous cell or adenocarcinoma. Squamous cell refers to cancers that originate in the cells that line the esophagus; adenocarcinoma begins in the part of the esophagus that joins the stomach.

Symptoms of Esophageal Cancer

Some people do not notice any symptoms until late in the disease. However, symptoms may include:

  • Difficulty swallowing
  • Hoarseness or long-lasting cough
  • Regurgitating blood
  • Weight loss with unknown cause
  • Pain in the throat or back
  • Vomiting

Causes of Esophageal Cancer

The causes are not fully understood, but scientists have discovered several likely contributing factors. These include:

  • Advancing age. People over age 60 are more likely to develop the disease.
  • Gender. This cancer is more common in men than women.
  • Tobacco use. Smoking cigarettes, cigars, pipes, or using snuff or chewing tobacco greatly increases risk. For those who both smoke and drink, the risk is highest.
  • Acid reflux. When stomach acids flow back into the esophagus, irritation occurs. Over time, this irritation can lead to problems, including a condition called Barrett's esophagus, where cell changes often lead to cancer.
  • Previous history of head or neck cancers.
  • An unhealthy lifestyle, which means being overweight or eating a diet low in fruits, vegetables, and whole grains.

Refer a Patient

Call: 617.414.5600
Fax: 617.638.7382

Diagnostic Tests

Treatments

Departments and Programs Who Treat This Condition

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A program within the Cancer Center providing diagnosis and treatment for thoracic cancers, including lung and chest tumors, with coordinated care across specialties to support eva…
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Advanced thoracic & cardiothoracic surgery that treats lung, esophageal, and mediastinal conditions, as well as specialized chest surgery for non-cardiac procedures using minimall…
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A department providing respiratory and lung medicine, including diagnosis and treatment for asthma, allergies, COPD, and other breathing conditions, with ongoing care to support l…
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An oncology department using advanced radiation therapy to treat cancer, with personalized planning and care to target tumors while protecting surrounding healthy tissue.
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A program within the Cancer Center providing diagnosis and treatment for cancers of the gastrointestinal system, including stomach, colon, and esophageal cancers, with coordinated…