A stem cell transplant is a procedure that uses stem cells to replace blood cells in the bone marrow that have been damaged or destroyed by chemotherapy, radiation or disease. For patients receiving a stem cell transplant, the first step is to lower the amount of cancer present in the patient’s body by induction treatment. After induction treatment, stem cells are harvested from the patient’s blood or bone marrow. Once harvested, the cells are frozen. After the stem cells have been removed, the patient receives high-dose chemotherapy to kill any leftover myeloma cells. The treatment also kills all of the remaining normal bone marrow cells. The frozen stem cells are then thawed and given back to the patient through an intravenous line in a process similar to a blood transfusion. The stem cells travel to the bone marrow where they begin to make new blood cells.