(She/Her)
Deepu Madduri, MD is the Compound Development Team Leader for CARVYKTI at Johnson and Johnson. Most recently, she served as a Senior Medical Director for the CARVYKTI team. As the study responsible physician for CART-1, Deepu provided invaluable leadership to drive the clinical strategy for global filing plans, navigating health authority reviews and securing the initial approval of CARVYKTI in key markets. Additionally, Deepu was the Study Responsible Physician for CART-6, a collaborative study with EMN. Despite challenges, Deepu successfully initiated and is rapidly enrolling patients into the study, overcoming regulatory hurdles and operational complexities. She played a key role in strategic planning to help secure the US IND clearance and has been working with various vein to vein and supply chain stakeholders to navigate through the logistics of initiating the clinical manufacturing outside of Raritan. Deepu has also provided clinical and key KOL stakeholder support for the successful CART-4 ODAC meeting.
Prior to joining J&J, Deepu was an Assistant Professor of Medicine at the Tisch Cancer Institute and the Icahn School of Medicine at Mount Sinai in New York City. There, she was an Associate Director of the Cellular Therapy Service and Director of Clinical Operations at the Myeloma Center of Excellence Program. Her research focused primarily on clinical management of plasma cell dyscrasias with a strong emphasis on relapsed and refractory multiple myeloma and was instrumental in starting the myeloma CAR T-cell program at Mount Sinai. Deepu was the lead investigator in various CART-T and bispecific programs at Mount Sinai including the CARTITUDE-1 program. Her work at Mount Sinai has been published in various journals.
Deepu completed her fellowship training in Blood and Bone Marrow Transplantation at Stanford Hospital in Palo Alto, CA. Prior to that, she completed her fellowship training in Hematology and Oncology at UCLA, Harbor campus and her Internal Medicine residency at St. Mary’s Medical Center/Harbor UCLA. She received her MD degree at the University of Oklahoma and grew up in Tulsa, Oklahoma.
Deepu currently lives in San Francisco, CA and she continues to see myeloma patients at Stanford Hospital as an Adjunct Faculty. In addition, she enjoys spending time traveling, going on hikes, and playing board games with her daughter, Sofia, and her husband, Pavan.