Weather Advisory: Temporary Door Closure

Due to extreme cold, access through the Moakley Building's entrance off Boston Medical Center Place will be temporarily closed from 5 p.m. Friday, Jan. 30, through 7 a.m. Monday, Feb. 2.

All patients and visitors should use the main entrance for the Menino and Yawkey Buildings during this time. The hospital remains open and operating as normal.

We appreciate your patience as we take these precautions during severe winter weather.

Sprache

TRA 2P – TIMI 50

TRA 2P – TIMI 50: Trial to Assess the Effects of SCH 530348 in Preventing Heart Attack and Stroke in Patients With Atherosclerosis

Sponsor: Schering Plough

Investigators: Carlos Kase MD (principal), Viken Babikian MD, Jose Romero MD

Trial results available here

This was a large clinical trial (with 26,449 patients) that evaluated whether the addition of SCH 530348 (Vorapaxar) to existing standard of care will yield additional benefit in prevention of heart attacks and strokes. In stable patients with a history of atherothrombosis, study results showed decreased deaths from cardiovascular disease, MI and stroke incidence and increased moderate and severe bleeding when added to standard of care. It appears to reduce recurrent atherothrombosis, caution is patient selection is needed due to increase bleeding.