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Stroke & Cerebrovascular Center

Our Team


Boston Medical Center
Shapiro Center
7th Floor, Suite 7B
725 Albany Street
Boston, MA 02118

Call: 617.638.8456
Fax: 617.638.8465

Jose Rafael Romero, MD

Associate Professor of Neurology
Boston University School of Medicine

CV Highlights

CV Highlights

Medical School
Escuela Colombiana de Medicina- Universidad El Bosque, Colombia (1995)

Research Fellowship
Brigham and Women's Hospital (1999)

Research Fellowship
Beth Israel Deaconess Medical Center (2000)

Cleveland Clinic Foundation, Cleveland (2001)

Neurology, Boston Medical Center (2005)

Vascular Neurology, Boston Medical Center (2006)

Board Certification
Neurology, Vascular Neurology

Special Interests
Stroke, Neurorehabilitation, Transcranial Magnetic Stimulation, Neurosonology

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Dr. Jose Romero earned his MD degree in Bogota, Colombia from the Escuela Colombiana de Medicine, Universidad El Bosque, in 1996 after graduating first in his class. After graduation he was involved in research in studies involving Transcranial Magnetic Stimulation and brain mapping techniques at the Department of Anesthesia, Brigham and Women's Hospital and The Laboratory for Brain Stimulation, Beth Israel Deaconess Center, in Boston, MA.

Dr. Romero completed his medical internship at Cleveland Clinic Foundation, Ohio, and his Neurology residency at Boston Medical Center. He then pursued his subspecialty in Vascular Neurology at the same institution and joined the Department of Neurology as faculty in 2006.

Dr. Romero is board certified by the American Board of Psychiatry and Neurology in Neurology (2007) and also board certified in the subspecialty of Vascular Neurology (2008).

 His professional and research interests are in cerebrovascular disease, with a special interest in carotid artery disease, subclinical atherosclerosis, stroke epidemiology and neurosonology. He is currently conducting research activities as investigator in the Framingham Heart Study, and is participating in several multicenter NIH-sponsored studies. He has presented his research at national and international meetings, authored several peer-reviewed publications and book chapters and is a reviewer for recognized journals, including Stroke.

Dr. Romero is committed to providing comprehensive and compassionate care for his patients, with a special interest in population minorities.

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Lau H, Coffey C, Kase CS, Babikian VL, Pikula A, Romero JR, Nguyen T, Benavente OR, on behalf of the SPS3 investigators. Clinical Trial Participation and Health Behavior Modification: Secondary Prevention of Small Subcortical Strokes (SPS3). J Neurological Disorders and Stroke. February 6, 2015.

Shoamanesh A, Preis SR, Beiser AS, Vasan RS, Benjamin EJ, Kase CS, Wolf PA, DeCarli C, Romero JR, Seshadri S.
Inflammatory biomarkers, cerebral microbleeds, and small vessel disease: Framingham Heart Study. Neurology 2015 Feb 24;84(8):825-32.

Romero JR, Lau H, Winters MR, Pikula A, Nguyen TN, Kase CS, Babikian VL. Disparities in acute stroke care: role of race and insurance status. Global J of Epid and Public Health (Dec 2014); 1(2): 35-41.

Shoamanesh A, Masoud H, Furey K, Duerfeldt K, Lau H, Romero JR, Pikula A, Teal P, Nguyen TN, Kase CS, Babikian VL. Larger a1/m1 diameter ratio predicts embolic anterior cerebral artery territorial stroke. Stroke 2014;45(9):2798-800

Shoamanesh A, Romero JR, Kase CS. Spontaneous cervical spinal epidural hematoma mimicking acute stroke. Can J Neurol Sci 2014;41(4):533-4.

Romero JR, Preis SR, Beiser A, DeCarli C, Viswanathan A, Martinez-Ramirez S, Kase CS, Wolf PA, Seshadri S. Risk factors, stroke prevention treatments, and prevalence of cerebral microbleeds in the Framingham Heart Study. Stroke 2014;45(5):1492-4.

Romero JR, Mercado M, Beiser AS, Pikula A, Seshadri S, Kelly-Hayes M, Wolf PA, Kase CS. Transient global amnesia and neurological events: the framingham heart study. Front Neurol 2013;4:47.

Romero JR, Wolf PA.  Epidemiology of Stroke: Legacy of the Framingham Heart Study. Glob Heart. 2013;8(1):67-75.

Romero JR, Preis SR, Beiser AS, DeCarli C, Lee DY, Viswanathan A, Benjamin EJ, Fontes J, Au R, Pikula A, Wang J, Kase CS, Wolf PA, Irrizary MC, Seshadri S.
Lipoprotein Phospholipase A2 and Cerebral Microbleeds in the Framingham Heart Study. Stroke September 2012

Lioutas V, Romero JR, Kleinman MS, Wang JW, Perloff MD. Clinical Reasoning: a 54-year-old man with unilateral weakness and vascular risk factors.  Neurology 2012;79(4):e28-32.

Fornage M, Debette S, Bis JC, Schmidt H, Ikram MA, Dufouil C, Sigurdsson S, Lumley T, DeStefano AL, Fazekas F, Vrooman HA, Shibata DK, Maillard P, Zijdenbos A, Smith AV, Gudnason H, de Boer R, Cushman M, Mazoyer B, Heiss G, Vernooij MW, Enzinger C, Glazer NL, Beiser A, Knopman DS, Cavalieri M, Niessen WJ, Harris TB, Petrovic K, Lopez OL, Au R, Lambert JC, Hofman A, Gottesman RF, Garcia M, Heckbert SR, Atwood LD, Catellier DJ, Uitterlinden AG, Yang Q, Smith NL, Aspelund T, Romero JR, Rice K, Taylor KD, Nalls MA, Rotter JI, Sharrett R, van Duijn CM, Amouyel P, Wolf PA, Gudnason V, van der Lugt A, Boerwinkle E, Psaty BM, Seshadri S, Tzourio C, Breteler MM, Mosley TH, Schmidt R, Longstreth WT, DeCarli C, Launer LJ. Genome-wide association studies of cerebral white matter lesion burden: the CHARGE consortium.
Ann Neurol 2011;69(6):928-39.

Romero JR, Ramirez DM, Aglio LS, Gugino LD. Brain mapping using transcranial magnetic stimulation. Neurosurg Clin N Am. 2011;22(2):141-52, vii.

Nguyen TN, Babikian VL, Romero JR, Pikula A, Kase CS, Jovin TG, Norbash AM. Intra-arterial treatment methods in acute stroke therapy. Frontiers in Endovascular and Interventional Neurology 2011;2:1-10.

Petrea RE, Koyfman F, Pikula A, Romero JR, Viereck J, Babikian VL, Kase CS, Nguyen TN. Acute Stroke, Catheter Related Venous Thrombosis, and Paradoxical Cerebral Embolism: Report of Two Cases. J Neuroimaging 2011;31.

Debette S, Beiser A, DeCarli C, Au R, Himali JJ, Kelly-Hayes M, Romero JR, Kase CS, Wolf PA, Seshadri S. Association of MRI markers of vascular brain injury with incident stroke, mild cognitive impairment, dementia, and mortality: the Framingham Offspring Study. Stroke 2010;41(4):600-6.

Romero JR, Beiser A, Seshadri S, Benjamin EJ, Polak JF, Vasan RS, Au R, Decarli C, Wolf PA. Carotid Artery Atherosclerosis, MRI Indices of Brain Ischemia, Aging, and Cognitive Impairment. The Framingham Study. Stroke 2009;40.

Romero JR, Frey JL, Schwamm LH, Demaerschalk BM, Chaliki HP, Parikh G, Burke RF, Babikian VL. Cerebral ischemic events associated with 'bubble study' for identification of right to left shunts. Stroke 2009;40(7):2343-8.

Romero JR,  Pikula A, Nguyen TN,  Nien YL,  Norbash A, Babikian VL. Cerebral Collateral Circulation in Carotid Artery Disease. Current Cardiology Reviews 2009;5(4):279-288.

Romero JR, Pikula A. Carotid Artery Disease: Current Concepts on Endothelial Dysfunction and Matrix Remodeling. Current Drug Therapy 2009;4(3):202-213.

Romero JR, Vasan RS, Beiser AS, Polak JF, Benjamin EJ, Wolf PA, Seshadri S. Association of carotid artery atherosclerosis with circulating biomarkers of extracellular matrix remodeling: the Framingham Offspring Study. J Stroke Cerebrovasc Dis 2008;17(6):412-7.

Romero JR, Morris J, Pikula A. Stroke prevention: modifying risk factors. Ther Adv Cardiovasc Dis 2008;2(4):287-303.

Romero JR. Prevention of ischemic stroke: overview of traditional risk factors. Curr Drug Targets. 2007;8(7):794-801.

Romero JR, Sakai O, Rice MB, Babikian VL. Intracranial hemorrhage sparing meningioma in an anticoagulated patient. J Neuroimaging. 2007;17(3):246-50.

Romero JR, Babikian VL, Katz DI, Finklestein SP. Neuroprotection and stroke rehabilitation: modulation and enhancement of recovery. Behav Neurol 2006;17(1):17-24.

Kahn JH, Viereck J, Kase C, Jeerakathil T, Romero R, Mehta SD, Kociol R, Babikian V. The use of intravenous recombinant tissue plasminogen activator in acute ischemic stroke. J Emerg Med 2005;29(3):273-7

Wagner T, Gangitano M, Romero R, Theoret H, Kobayashi M, Anschel D, Ives J, Cuffin N, Schomer D, Pascual-Leone A. Intracranial measurement of current densities induced by transcranial magnetic stimulation in the human brain. Neurosci Lett 2004;354(2):91-4.

Gangitano M, Valero-Cabré A, Tormos JM, Mottaghy FM, Romero JR and Pascual-Leone Á. Modulation of input¯output curves by low and high frequency repetitive transcranial magnetic stimulation of the motor cortex. Clin Neurophysiol 2002; 113:1249-1257.

Romero JR, Anschel D, Sparing R, Gangitano M, Pascual-Leone A. Subthreshold low frequency transcranial magnetic stimulation selectively decreases facilitation in the motor cortex. Clin Neurophysiol 2002;113 (1):101-107.

Aglio LS, Romero R, Desai S, Ramirez M, Gonzalez AA, Gugino LD. The use of transcranial magnetic stimulation for monitoring descending spinal cord motor function. Clin Electroencephalogr 2002;33(1):30-41.

Aglio LS, Kraus KH, Desai S, Romero R, Ramirez M, Levy WJ, Gugino LD. Efficacious use of a cap shaped coil for transcranial magnetic stimulation of descending motor paths. Clin Electroencephalogr. 2002;33(1):21-9.

Gugino LD, Romero JR, Aglio L, Titone D, Ramirez M, Pascual-Leone A, Grimson E, Weisenfeld N, Kikinis R, Shenton ME. Transcranial magnetic stimulation coregistered with MRI: a comparison of a guided versus blind stimulation technique and its effect on evoked compound muscle action potentials. Clin Neurophysiol 2001;112(10):1781-92.

Gugino LD, Aglio L, Raymond SA, Romero JR, Ramirez M, Gonzalez AA, Black PM. Intraoperative cortical function localization techniques. In: Techniques in neurosurgery. 2001 Lippincott Williams & Wilkins, Inc., Philadelphia. Vol. 7, No. 1, pp. 19-32.

Gugino LD, Aglio L, Potts G, Grimson WE, Shenton ME, Kikinis R, Alexander III E, Gonzalez AA, Romero JR, Ettinger GJ, Cote W, Leventon ME, Black PM. Perioperative use of Transcranial magnetic stimulation. In: Techniques in neurosurgery. 2001 Lippincott Williams & Wilkins, Inc., Philadelphia. Vol. 7, No. 1, pp. 33-51.


Call: 617.638.8456
Fax: 617.638.8465
Email: stroke@bmc.org

Boston Medical Center
Department of Neurology
Shapiro Center
7th Floor, Suite 7B
725 Albany Street
Boston, MA 02118

For Research Information

Contact Helena Lau,
Call: 617.414.1171
Fax: 617.638.5354
stroke@bmc.org or

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