Stroke & Cerebrovascular Center
Boston Medical Center
Director, Interventional Neuroradiology & Neurology
Fellowship in Interventional Neuroradiology, Centre Hospitalier de I´Universite de Montreal, Montreal, Canada (2007)
Thanh Nguyen, MD, FRCP is the director of interventional neurology/neuroradiology at Boston Medical Center (BMC) and associate professor of neurology, radiology, and neurosurgery at Boston University School of Medicine (BUSM).
After receiving her medical degree from McGill University Faculty of Medicine in Canada, Dr. Nguyen performed her neurology residency at Massachusetts General Hospital and Brigham and Women's Hospital in Boston. Following her fellowship in vascular neurology and neurocritical care at Massachusetts General Hospital, she completed a fellowship in interventional neuroradiology (INR) involving more than 1,000 INR procedures at Centre Hospitalier de l'Universite de Montreal with the internationally renowned experts Jean Raymond and others. She has now been involved in a total of more than 2,000 INR procedures, including more than 400 brain aneurysm coilings.
Dr. Nguyen's clinical and research interests include acute intra-arterial therapies for stroke and evaluating outcome and complications of aneurysm coiling. Other clinical interests include neurocritical care, pre-operative embolization for head and neck tumors, carotid and intracranial artery stenosis, subarachnoid hemorrhage, spinal vascular interventions, traumatic carotid and vertebral dissection, vertebroplasty and kyphoplasty for acute spinal fractures.
Dr. Nguyen has authored more than 60 peer-reviewed publications and contributed to many book chapters including an INR atlas. She is a reviewer for the neuroendovascular section of 8 neuroscience journals and has made more than 70 presentations at scientific meetings on a national and international level. She is Associate Editor of the Interventional Neurology Journal.
She was elected board member of the Society of Vascular and Interventional Neurology (SVIN) in 2008, re-elected in 2014 and Research Chair of the SVIN in 2013. She was awarded Fellow of the SVIN (FSVIN) in 2012 based on her contributions to the field of Interventional Neurology.
Nguyen TN, Masoud H, Tarlov N, Holsapple J, Chin LS, Norbash AM. Expanding endovascular therapy of very small ruptured aneurysms with the 1.5mm coil. Interventional Neurology 2015;4(1-2):59-63.
Masoud H, Nguyen TN, Thatcher J, Barest G, Norbash AM. Duplication of the posterior cerebral artery and the true "fetal" variant. Interventional Neurology 2015;4(1-2):64-67.
Lau H, Coffey C, Kase CS, Babikian VL, Pikula A, Romero JR, Nguyen T, Benavente OR, on behalf of the SPS3 investigators. Clinical Trial Participation and Health Behavior Modification: Secondary Prevention of Small Subcortical Strokes (SPS3). J Neurological Disorders and Stroke. February 6, 2015.
Linfante I, Starosciak AK, Walker GR, Dabus G, Castonguay AC, Gupta R, Sun CJ, Martin C, Holloway WE, Mueller-Kronast N, English JD, Malisch TW, Marden FA, Bozorgchami H, Xavier A, Rai AT, Froehler MT, Badruddin A, Nguyen TN, Taqi MA, Abraham MG, Janardhan V, Shaltoni H, Novakovic R, Yoo AJ, Abou-Chebl A, Chen PR, Britz GW, Kaushal R, Nanda A, Issa MA, Nogueira RG, Zaidat OO. Predictors of poor outcome despite recanalization: a multiple regression analysis of the NASA registry. J Neurointerv Surg. 2015 Jan 6. pii: neurintsurg-2014-011525.
Romero JR, Lau H, Winters MR, Pikula A, Nguyen TN, Kase CS, Babikian VL. Disparities in acute stroke care: role of race and insurance status. Global J of Epid and Public Health (Dec 2014); 1(2): 35-41.
Castonguay AC, Zaidat OO, Novakovic R, Nguyen TN, Taqi MA, Gupta R, Sun CHJ, Martin C, Holloway WE, Mueller-Kronast N, English JE, Linfante I, Dabus G, Malisch TW, Marden FA, Bozorgchami H, Xavier A, Rai AT, Froehler MT, Badruddin A, Abraham MG, Janardhan V, Shaltoni H, Yoo AJ, Abou-Chebl A, Chen PR, Britz GW, Kaushal R, Nanda A, Issa MA, Nogueira RG. Influence of Age on Clinical and Revascularization Outcomes in the North American Solitaire: Stent-Retriever Acute Stroke Registry. Stroke 2014;45:3631-6.
Shoamanesh A, Masoud H, Furey K, Duerfeldt K, Lau H, Romero JR, Pikula A, Teal P, Nguyen TN, Kase CS, Babikian VL. Larger a1/m1 diameter ratio predicts embolic anterior cerebral artery territorial stroke. Stroke 2014;45(9):2798-800
Prabhakaran S1, Jovin TG, Tayal AH, Hussain MS, Nguyen TN, Sheth KN, Terry JB, Nogueira RG, Horev A, Gandhi D, Wisco D, Glenn BA, Ludwig B, Clemmons PF, Cronin CA, Tian M, Liebeskind D, Zaidat OO, Castonguay AC, Martin C, Mueller-Kronast N, English JD, Linfante I, Malisch TW, Gupta R. Posttreatment Variables Improve Outcome Prediction after Intra-Arterial Therapy for Acute Ischemic Stroke. Cerebrovasc Dis. 2014 18;37(5):356-363.
Sun CH, Ribo M, Goyal M, Yoo AJ, Jovin T, Cronin CA, Zaidat O, Nogueira R, Nguyen T, Hussain S, Menon BK, Mehta B, Jindal G, Horev A, Norbash A, Leslie-Mazwi T, Wisco D, Gupta R. Door-to-puncture: a practical metric for capturing and enhancing system processes associated with endovascular stroke care, preliminary results from the rapid reperfusion registry. J Am Heart Assoc. 2014;3(2):e000859.
Abou-Chebl A, Zaidat OO, Castonguay AC, Gupta R, Sun CH, Martin CO, Holloway WE, Mueller-Kronast N, English JD, Linfante I, Dabus G, Malisch TW, Marden FA, Bozorgchami H, Xavier A, Rai AT, Froehler MT, Badruddin A, Nguyen TN, Taqi M, Abraham MG, Janardhan V, Shaltoni H, Novakovic R, Yoo AJ, Chen PR, Britz GW, Kaushal R, Nanda A, Issa MA, Nogueira RG. North American SOLITAIRE Stent-Retriever Acute Stroke Registry: Choice of Anesthesia and Outcomes. Stroke 2014;45:1396-401.
Nguyen TN, Malisch TW, Zaidat OO; On behalf of the North American Solitaire Acute Stroke Registry. Response to Letter Regarding Article, "Balloon Guide Catheter Improves Revascularization and Clinical Outcomes With the Solitaire Device: Analysis of the North American Solitaire Acute Stroke Registry" Stroke 2014 Mar 13.
Nogueira RG, Gupta R, Jovin TG, Levy EI, Liebeskind DS, Zaidat OO, Rai A, Hirsch JA, Hsu DP, Rymer MM, Tayal AH, Lin R, Natarajan SK, Nanda A, Tian M, Hao Q, Kalia JS, Chen M, Abou-Chebl A, Nguyen TN, Yoo AJ. Predictors and clinical relevance of hemorrhagic transformation after endovascular therapy for anterior circulation large vessel occlusion strokes: a multicenter retrospective analysis of 1122 patients. J Neurointerv Surg. 2014 Jan 8
Nguyen TN, Malisch T, Castonguay AC, Gupta R, Sun CHJ, Martin CO, Holloway WE, Mueller-Kronast N, English JD, Linfante I, Dabus G, Marden FA, Bozorgchami H, Xavier A, Rai AT, Froehler MT, Badruddin A, Taqi M, Abraham MG, Janardhan V, Shaltoni H, Novakovic R, Yoo AJ, Abou-Chebl A, Chen PR, Britz GW, Kaushal R, Nanda A, Issa MA, Masoud H, Nogueira RG, Norbash AM, Zaidat OO. Balloon Guide Catheter Improves Revascularization and Clinical Outcomes With the Solitaire Device. Analysis of the North American Solitaire Acute Stroke Registry. Stroke 2014;45:141-5.
Masoud H, Tang E, Nguyen T, Norbash A. Spontaneous Rupture of a Cavernous Internal Carotid Artery Aneurysm Causing Direct Carotid-Cavernous Fistula. The Stroke Interventionalist 2014.
Zaidat OO, Castonguay AC, Gupta R, Sun CH, Martin C, Holloway WE, Mueller-Kronast N, English JD, Linfante I, Dabus G, Malisch TW, Marden FA, Bozorgchami H, Xavier A, Rai AT, Froehler MT, Badruddin A, Nguyen TN, Taqi MA, Abraham MG, Janardhan V, Shaltoni H, Novakovic R, Yoo AJ, Abou-Chebl A, Chen PR, Britz GW, Kaushal R, Nanda A, Issa MA, Nogueira RG. North American Solitaire Stent Retriever Acute Stroke registry: post-marketing revascularization and clinical outcome results. J Neurointerv Surg 2014;6:584-8.
Masoud H, Nguyen T. Intracranial Stenting for Stroke Prevention–The Lessons from SAMMPRIS. The Stroke Interventionalist. 2013:1;2.
Zaidat OO, Castonguay AC, Nguyen TN, Becker KJ, Derdeyn CP, Nelson PK, Amarenco P, Brott TG. Impact of SAMMPRIS on the future of intracranial atherosclerotic disease management: polling results from the ICAD symposium at the International Stroke Conference. J Neurointerv Surg. 2014;6:225-30.
Sheth KN, Terry JB, Nogueira RG, Horev A, Nguyen TN, Fong AK, Gandhi D, Prabhakaran S, Wisco D, Glenn BA, Tayal AH, Ludwig B, Hussain MS, Jovin TG, Clemmons PF, Cronin C, Liebeskind DS, Tian M, Gupta R. Advanced modality imaging evaluation in acute ischemic stroke may lead to delayed endovascular reperfusion therapy without improvement in clinical outcomes. J Neurointerv Surg 2012 Oct 16.
Nguyen TN, Zaidat OO, Edgell RC, Janjua N, Yavagal DR, Xavier AR, Kirmani JF, Liebeskind DS, Nogueira RG, Vora NA, Sims JR, Lynch JR, Fitzsimmons BF, Wolfe TJ, Chen M, Badruddin A, Zahuranec DB, McDonagh DL, Janardhan V, Bastan B, Madden JA, Sanossian N, Gupta R, Lazzaro MA, Jovin TG, Abou-Chebl A, Linfante I, Hussain SI. Vascular neurologists and neurointerventionalists on endovascular stroke care: Polling results. Neurology. 2012 Sep 25;79(13 Suppl 1):S5-S15.
Lazzaro MA, Novakovic RL, Alexandrov AV, Darkhabani Z, Edgell RC, English J, Frei D, Jamieson DG, Janardhan V, Janjua N, Janjua RM, Katzan I, Khatri P, Kirmani JF, Liebeskind DS, Linfante I, Nguyen TN, Saver JL, Shutter L, Xavier A, Yavagal D, Zaidat OO. Developing practice recommendations for endovascular revascularization for acute ischemic stroke.
Janjua N, Katzan I, Badruddin A, Nguyen TN, Abou-Chebl A, Zaidat OO. Endovascular comprehensive stroke center designation parameters. Neurology. 2012 Sep 25;79(13 Suppl 1):S239-42.
Tarlov N, Nien YL, Zaidat OO, Nguyen TN. Periprocedural management of acute ischemic stroke intervention.
Singh J, Nguyen TN. Endovascular and neurosurgical management of acute ischemic stroke. Emerg Med Clin North Am. 2012 Aug;30(3):695-712. doi: 10.1016/j.emc.2012.06.002.
Tarlov N, Norbash AM, Nguyen TN. The safety of anticoagulation in patients with intracranial aneurysms. J Neurointerv Surg 2012 Jun 7.
Gupta R, Horev A, Nguyen T, Gandhi D, Wisco D, Glenn BA, Tayal AH, Ludwig B, Terry JB, Hussain MS, Gershon RY, Jovin T, Clemmons PF, Frankel MR, Cronin CA, Tian M, Sheth KN, Nogueira RG, Anderson AM, Belagaje SR. Higher volume endovascular stroke centers have faster times to treatment, higher reperfusion rates and higher rates of good clinical outcomes. J Neurointerv Surg 2012 May 13.
Qureshi AI, Al-Senani FM, Husain S, Janjua NA, Lanzino G, Lavados PM, Nguyen T, Raymond J, Shah QA, Suarez JI, Suri MF, Tolun R. Intracranial angioplasty and stent placement after stenting and aggressive medical management for preventing recurrent stroke in intracranial stenosis (SAMMPRIS) trial: present state and future considerations. J Neuroimaging. 2012;22(1):1-13.
Nguyen TN, Lazzaro MA, Qureshi AI. New standards for intracranial atherosclerotic disease treatment. Front Neurol. 2011;2:77.
Westwood AJ, Nguyen TN. Teaching NeuroImages: TIA from an air embolism. Neurology 2011;77(21):e123.
Voetsch B, Tarlov N, Nguyen TN, Defusco C, Barest GD, Norbash A, Green DM, Burns JD. Asymmetric Posterior Reversible Encephalopathy Syndrome Complicating Hemodynamic Augmentation for Subarachnoid Hemorrhage-Associated Cerebral Vasospasm. Neurocrit Care. 2011 Oct 1.
Nguyen TN, Babikian VL, Romero JR, Pikula A, Kase CS, Jovin TG, Norbash AM. Intra-arterial treatment methods in acute stroke therapy. Frontiers in Endovascular and Interventional Neurology 2011;2:1-10.
Nguyen TN, Zaidat OO, Gupta R, Nogueira RG, Tariq N, Kalia JS, Norbash AM, Qureshi AI. Balloon Angioplasty for Intracranial Atherosclerotic Disease: Periprocedural Risks and Short Term Outcomes in a Multicenter Study. Stroke 2011;42:107-111.
Gupta R, Tayal AH, Levy EI, Cheng-Ching E, Rai A, Liebeskind DS, Yoo AJ, Hsu DP, Rymer MM, Zaidat OO, Lin R, Natarajan SK, Nogueira RG, Nanda A, Tian M, Hao Q, Abou-Chebl A, Kalia JS, Nguyen TN, Chen M, Jovin TG. Intra-arterial thrombolysis or Stent Placement during Endovascular Treatment for Acute Ischemic Stroke Leads to the Highest Recanalization Rate: Results of a Multi-center Retrospective Study. Neurosurgery 2011 Feb 16.
Petrea RE, Koyfman F, Pikula A, Romero JR, Viereck J, Babikian VL, Kase CS, Nguyen TN. Acute Stroke, Catheter Related Venous Thrombosis, and Paradoxical Cerebral Embolism: Report of Two Cases. J Neuroimaging 2011;31.
Natarajan SK, Dandona P, Karmon Y, Yoo AJ, Kalia JS, Hao Q, Hsu DP, Chaudhuri A, Paluch RA, Khalessi AA, Meng H, Hopkins LN, Ogilvy CS, Fiorella DJ, Bendok BR, Nguyen TN, Rymer MM, Nanda A, Liebeskind DS, Zaidat OO, Nogueira RG, Siddiqui AH, Levy EI. Blood Glucose Predicts Adverse Outcomes after Endovascular Acute Ischemic Stroke Therapy. J Neurosurg 2011
Babikian VL, Nguyen TN. Improving outcome of acute revascularization procedures. Stroke 2010;41:577.
Kase CS, Nguyen TN. The clinical conundrum of convexal subarachnoid hemorrhage. Neurology 2010;74:874-875.
Abou-Chebl A, Lin R, Hussain MS, Jovin TG, Levy EI, Liebeskind DS, Yoo AJ, Hsu DP, Rymer MM, Tayal AH, Zaidat OO, Natarajan SK, Nogueira RG, Nanda A, Tian M, Hao Q, Kalia JS, Nguyen TN, Chen M, Gupta R. Conscious sedation versus general anesthesia during endovascular therapy for acute anterior circulation stroke: preliminary results from a retrospective, multicenter study. Stroke 2010;41:1175-9.
Nguyen TN, Chin LS, Souza R,Norbash AM. Transvenous embolization of a ruptured cerebral arteriovenous malformation with en-passage arterial supply: initial case report. J Neuroint Surg 2010.
Karakis I, Nguyen TN, Babikian VL, Norbash A. Balloon angioplasty of the anterior cerebral artery A2 segment for recurrent, symptomatic atherosclerotic disease. Journal of Neurosurgery 2010;112(3):582-4
Romero JR, Pikula A, Nguyen TN, Nien YL, Norbash A, Babikian VL. Cerebral Collateral Circulation in Carotid Artery Disease Current Cardiology Reviews 2009;5(4):279-288
Nguyen TN, Raymond J, Guilbert F, Roy D, Mahmoud M, Berube M, Weill A. Association of endovascular therapy of very small ruptured aneurysms with higher rates of procedure-related rupture. J Neurosurg 2008;108:1088-1092.
Nguyen TN, Raymond J, Mahmoud M, Weill A, Roy D, Guilbert F. Vertebral artery stump syndrome. J Neurol Neurosurg Psychiatry 2008;79:91-2.
Pikula A, Almodovar J, Nguyen TN. Cerebral arteriovenous malformation in hereditary hemorrhagic telangiectasia. Neurology 2009;72;e45.
Chen M, Nguyen T. Emerging subspecialties in neurology: endovascular surgical neuroradiology. Neurology 2008;70(6):e21-4 Review.
Nguyen TN, Raymond J. The Color of Ruptures. Stroke 2008;39:e136.
Nguyen TN, Lanthier S, Roy D. Iatrogenic arterial perforation during acute stroke interventions. Am J Neuroradiol 2008;29(5):974-5.
Nguyen TN, Raymond J, Roy D, Chagnon M, Weill A, Iancu-Gontard D, Guilbert F. Endovascular treatment of pericallosal aneurysms. J Neurosurg 2007;107:973-6.
Raymond J, White P, Kallmes DF, Spears J, Marotta T, Roy D, Guilbert F, Weill A, Nguyen T, Molyneux AJ, Cloft H, Cekirge S, Saatci I, Bracard S, Meder JF, Moret J, Cognard C, Qureshi AI, Turk AS, Berenstein A. ICONE: An International Consortium of Neuro Endovascular Centres. Interv Neuroradiol. 2008:30;14(2):203-8.
Nguyen TN, Roy D, Guilbert F, Raymond J, Weill A. Endovascular trapping of a vertebral artery segment to control PICA origin tearing. J Neuroimaging 2008;18:418-21.
Raymond J, Roy D, Weill A, Guilbert F, Nguyen T, Molyneux AJ, Fox AJ, Johnston SC, Cognard C, Pierot L, Meder JF, Rouleau I; Trial on Endovascular Aneurysm Management (TEAM) collaborative group. Unruptured intracranial aneurysms: their illusive natural history and why subgroup statistics cannot provide normative criteria for clinical decisions or selection criteria for a randomized trial. J Neuroradiol 2008;35(4):210-6.
Nguyen TN, Hoh BL, Amin-Hanjani S, Pryor JC, Ogilvy CS. Comparison of ruptured vs unruptured aneurysms in recanalization after coil embolization. Surg Neurol 2007;68(1): 19-23.
Raymond J, Nguyen T, Chagnon M, Gevry G; BSC and the Trial on Endovascular Aneurysm Management (TEAM) collaborative group. Unruptured Intracranial Aneurysms. Opinions of Experts in Endovascular Treatment Are Coherent,Weighted in Favour of Treatment, and Incompatible with ISUIA. Interv Neuroradiol. 2007;13(3):225-37.
Raymond J, Salazkin I, Gevry G, Nguyen TN. Interventional neuroradiology: the role of experimental models in scientific progress. AJNR Am J Neuroradiol 2007;28(3):401-5.
Iancu-Gontard D, Weill A, Guilbert F, Nguyen T, Raymond J, Roy D. Inter- and intraobserver variability in the assessment of brain arteriovenous malformation angioarchitecture and endovascular treatment results. Am J Neuroradiol 2007;28(3):524-7.
Nguyen TN, Badjatia N, Malhotra A, Gibbons FK, Qureshi MM, Greenberg SA. Factors predicting extubation success in patients with Guillain-Barré syndrome. Neurocrit Care 2006;5:230-4.
Cochrane TI, Nguyen TN. Swiss cheese brain. Neurology 2007;68:140.
Nguyen T, Koroshetz WJ. Intensive care management of ischemic stroke. Curr Neurol Neurosci Rep 2003;3:32-9.
Badjatia N, Nguyen TN, Koroshetz WJK. Critical Care of the Acute Ischemic Stroke Patient. In Critical Care Neurology and Neurosurgery. Ed. Suarez JI, Blackwell Publishing, 2003 (invited chapter).