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Center for Minimally Invasive Esophageal Therapies



At the Center for Minimally Invasive Esophageal Therapies at Boston Medical Center, we specialize in many of the latest and most effective treatments, including esophageal cryotherapy. Our team of highly trained and experienced specialists takes a collaborative approach to your treatment. We draw on medical expertise, state-of-the-art facilities and a patient-centered environment to provide you with the best medicine and the best medical care in New England.


Cryoablation, sometimes called cryotherapy, is a minimally invasive treatment used to destroy diseased cells in the esophagus caused by esophageal cancer and/or Barrett's esophagus. For cryoablation, a physician inserts a small tube (endoscope) through your mouth and into your esophagus. Once the endoscope is in place, liquid nitrogen is sprayed through the endoscope into the esophagus. The liquid nitrogen freezes the lining of your esophagus. The frozen cells die and are replaced by healthy cells. Cryoablation is used to treat Barrett's esophagus with high-grade dysplasia, and some early stage esophageal cancers. It can also be used to improve symptoms of advanced cancers. These symptoms include difficulty swallowing and bleeding.

How to Prepare

Tell your doctor if you have any allergies to medication or have had problems with anesthesia. Your doctor will give you any specific instructions about dietary or activity restrictions, as well as whether or not you should take your regular medications on the day of the procedure. Before treatment starts, your doctor will prescribe a medication that decreases stomach acid, such as Aciphex (rabeprazole), Nexium (esomeprazole) or Prilosec (omeprazole).

You will have cryoablation every three to eight weeks. The exact frequency depends on the specific problem in your esophagus and how it responds to the freezing treatments. Treatment ends when your doctor can find no abnormal tissue. You will be asked not to eat or drink after midnight on the night before your procedure. You may wish to ask a friend or family member to drive you to your procedure.

What to Expect

For the procedure, your doctor will examine the lining of your esophagus with an endoscope, which is a flexible, lighted tube with a video camera attached to it, by passing the endoscope through your mouth and throat. After the evaluation, your doctor will spray liquid nitrogen through the endoscope, destroying the diseased cells. After spraying the diseased cells, your doctor will remove the endoscope and the cryotherapy is completed. The cryotherapy procedure takes 10 to 15 minutes to complete.


After the procedure, you will be taken to a recovery area until you are awake and alert. Because of the use of a sedative, you will not be able to drive and should arrange for a ride home.

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Boston Medical Center
Center for Minimally Invasive Esophageal Therapies
Moakley Building
3rd Floor,
830 Harrison Avenue
Boston, MA 02118


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Boston Medical Center
88 East Newton Street, Suite 402
Boston, MA 02118
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