The Alpha-1 Center provides comprehensive care for patients and families with alpha-1 antitrypsin deficiency (AATD), the leading genetic cause of emphysema. Our multi-disciplinary team specializes in all aspects of care for AATD, including diagnosis, genetic counseling, and treatment, combining clinical care with research to enhance outcomes.



  ### Alpha-1 Center

- [Contact Us](#contact-us)
- [Programs and Services](#programs-and-services)
- [Treatments & Services](#treatments-services)
- [Our Team](#our-team)
 
   ## Contact Us

#####  Alpha-1 Center 

 

 [ 725 Albany St., Boston, MA 02118   
9th Floor, Suite 9B   
BMC, Shapiro Center ](https://www.google.com/maps/dir/725+Albany+Street,+Boston,+MA) 

 [617.638.7480](tel:617.638.7480) 

Monday-Friday - 8:00 AM - 5:00 PM

 

 

 [    ![](https://assets.bmc.org/transform/bfc9329a-5a2c-47fb-a7a2-c64d0d17dfba/img_1611?io=transform:fill,width:300,height:200&format=jpg)  

 ](/content/shapiro-center) 

 



 

  ## Programs and Services

  [### Cardiovascular Center

A department providing cardiology care for heart and vascular conditions, including coronary artery disease, heart failure, arrhythmias, valve disorders, and vascular disease, with coordinated services to support long-term heart health.

 

 

 ](/departments/cardiovascular-center)  ## Treatments & Services

 ### Infusions of Alpha-1 Antitrypsin

This may be given to patients whose bodies do not produce enough of it on their own.

 [Read more](/content/infusions-alpha-1-antitrypsin)

   ## Our Team

### Pulmonology

 

 ###  [Andrew A. Wilson, MD](https://www.bmc.org/about-us/directory/doctor/andrew-wilson-md) 

 Pulmonologist 


 

   ![Placeholder image for doctor](/themes/custom/bmc_base_theme/assets/images/placeholders/headshoticon-v2.svg)  ###  [Darrell Kotton, MD](https://www.bmc.org/about-us/directory/doctor/darrell-kotton-md) 

 Pulmonologist 


 

    ![](https://assets.bmc.org/transform/3f582a81-23d0-432d-ad8f-6666e9171276/Darrell-Kotton_102_2x3?io=transform:fill,width:333,height:500&format=jpg)   ###  [Joseph E. Kaserman, MD](https://www.bmc.org/about-us/directory/doctor/joseph-e-kaserman-md) 

 Pulmonologist 


 

    ![](https://assets.bmc.org/transform/d7e80135-dc75-4238-ae7b-c0e16d36a489/Kaserman-Joseph?io=transform:fill,width:333,height:500&format=jpg)   

 

 

 



### Gastroenterology

 

 ###  [Robert C. Lowe, MD](https://www.bmc.org/about-us/directory/doctor/robert-c-lowe-md) 

 Gastroenterologist 


 

    ![](https://assets.bmc.org/transform/530c2d1a-db54-4755-9a6c-1a48a1321826/Robert-Lowe_62_2x3?io=transform:fill,width:333,height:500&format=jpg)   ###  [David P. Nunes, MD](https://www.bmc.org/about-us/directory/doctor/david-p-nunes-md) 

 Gastroenterologist 


 

    ![](https://assets.bmc.org/transform/2f7ff196-d2c5-4d3a-aa97-82a46b09ff2a/Nunes_David_P_MD_Gastro?io=transform:fill,width:333,height:500&format=jpg)