Stroke & Cerebrovascular Center
Boston Medical Center
Professor and Chair, Radiology
Dr. Alexander Norbash joined Boston Medical Center in 2004 as Chairman and Professor of Radiology. He is an interventional neuroradiologist with an active endovascular neurosurgical practice, having performed more than 6000 endovascular neuroradiology procedures, including more than 400 aneurysms, and more than 300 stents. He is among the first clinician-interventionalists to develop and describe the technology of stenting for the carotid and intracranial arteries. Other clinical interests include endovascular aneurysm therapy, endovascular treatment of arteriovenous malformations, and percutaneous vertebroplasty and kyphoplasty.
Dr. Norbash has been active in developing many novel materials and devices for endovascular neurologic therapies, including ultrathin stent placement for the endovascular treatment of surgically created aneurysms, endovascular photoacoustic recanalization (EPAR) as an alternative non-chemical method for stroke thrombolysis, resorbable polymer stents, injectable polymer and hydrogel vascular embolic and occlusive compounds, and operator controllable remote-motion microcatheters. Other research interests include endovascular and interventional simulation systems.
Prior to joining Boston Medical Center, Dr. Norbash was Associate Professor of Radiology at Harvard Medical School, directed the Diagnostic and Interventional Neuroradiology Service at Brigham and Women's Hospital, and founded the Interventional Neuroradiology and Endovascular Neurosurgical practices at Brigham and Women's Hospital.
Dr. Norbash has more than 60 peer-reviewed manuscripts and 12 book chapters, and served as the 2007-08 President of the New England Roentgen Ray Society. He was recognized as a "Top Doctor" in Radiology by Boston Magazine in 2009, 2010, 2011, 2012, 2013, 2014 and by U.S. News and World Report in 2011.
Sun CH, Ribo M, Goyal M, Yoo AJ, Jovin T, Cronin CA, Zaidat O, Nogueira R, Nguyen T, Hussain S, Menon BK, Mehta B, Jindal G, Horev A, Norbash A, Leslie-Mazwi T, Wisco D, Gupta R. Door-to-puncture: a practical metric for capturing and enhancing system processes associated with endovascular stroke care, preliminary results from the rapid reperfusion registry. J Am Heart Assoc. 2014;3(2):e000859.
Nguyen TN, Malisch T, Castonguay AC, Gupta R, Sun CHJ, Martin CO, Holloway WE, Mueller-Kronast N, English JD, Linfante I, Dabus G, Marden FA, Bozorgchami H, Xavier A, Rai AT, Froehler MT, Badruddin A, Taqi M, Abraham MG, Janardhan V, Shaltoni H, Novakovic R, Yoo AJ, Abou-Chebl A, Chen PR, Britz GW, Kaushal R, Nanda A, Issa MA, Masoud H, Nogueira RG, Norbash AM, Zaidat OO. Balloon Guide Catheter Improves Revascularization and Clinical Outcomes With the Solitaire Device. Analysis of the North American Solitaire Acute Stroke Registry. Stroke 2014.
Masoud H, Tang E, Nguyen T, Norbash A. Spontaneous Rupture of a Cavernous Internal Carotid Artery Aneurysm Causing Direct Carotid-Cavernous Fistula. The Stroke Interventionalist 2014.
Forman HP, Larson DB, Kazerooni EA, Norbash A, Crowe JK, Javitt MC, Beauchamp NJ Jr. Masters of radiology panel discussion--is imaging in decline? AJR Am J Roentgenol. 2013 Jan;200(1):127-31
Norbash A, Hindson D, Heineke J. The accountable health care act of Massachusetts: mixed results for an experiment in universal health care coverage. J Am Coll Radiol. 2012;9(10):734-9.
Forman HP, Larson DB, Kazerooni EA, Norbash A, Crowe JK, Javitt MC, Beauchamp NJ Jr, Mendelson EB. Masters of radiology panel discussion: hyperefficient radiology--can we maintain the pace? AJR Am J Roentgenol 2012;199(4):838-43.
Forman HP, Larson DB, Kaye AD, Kazerooni EA, Norbash A, Crowe JK, Javitt MC, Beauchamp NJ Jr, Mendelson EB. Masters of radiology panel discussion: The future of the radiology job market. AJR Am J Roentgenol. 2012 Jul;199(1):127-32.
Li B, Behrman RH, Norbash AM. Comparison of topogram-based body size indices for CT dose consideration and scan protocol optimization. Med Phys 2012;39(6):3456-65. doi: 10.1118/1.4718569.
Tarlov N, Norbash AM, Nguyen TN. The safety of anticoagulation in patients with intracranial aneurysms. J Neurointerv Surg 2012 Jun 7.
Li B, Behrman RH, Norbash AM. Comparison of topogram-based body size indices for CT dose consideration and scan protocol optimization. Med Phys 2012;39(6):3456-65.
Norbash A, Klein LW, Goldstein J, Haines D, Balter S, Fairobent L, Miller DL on behalf of the members of the Multispecialty Occupational Health Group. The neurointerventional procedure room of the future: predicting likely innovations in design and function. J NeuroIntervent Surg 2011;3:266-271
Voetsch B, Tarlov N, Nguyen TN, Defusco C, Barest GD, Norbash A, Green DM, Burns JD. Asymmetric Posterior Reversible Encephalopathy Syndrome Complicating Hemodynamic Augmentation for Subarachnoid Hemorrhage-Associated Cerebral Vasospasm. Neurocrit Care. 2011 Oct 1.
Patel NV, Gounis MJ, Wakhloo AK, Noordhoek N, Blijd J, Babic D, Takhtani D, Lee SK, Norbash A. Contrast-Enhanced Angiographic Cone-Beam CT of Cerebrovascular Stents: Experimental Optimization and Clinical Application . AJNR 2011;32:137-144
Nguyen TN, Babikian VL, Romero JR, Pikula A, Kase CS, Jovin TG, Norbash AM. Intra-arterial treatment methods in acute stroke therapy. Frontiers in Endovascular and Interventional Neurology 2011;2:1-10.
Klein LW, Miller DL, Goldstein J, Haines D, Balter S, Fairobent L, Norbash A; On behalf of the members of the Multispecialty Occupational Health Group. The catheterization laboratory and interventional vascular suite of the future: Anticipating innovations in design and function. Catheter Cardiovasc Interv. 2011
Forman HP, Norbash A, Beauchamp NJ Jr, Thrall JH, Larson DB, Kazerooni EA, Hricak H, Monsees B, Javitt MC, Crowe JK. Masters of radiology panel discussion: Models for health care performance in radiology--how do we measure our productivity and ourselves? AJR Am J Roentgenol. 2011;196(1):130-5.
Nguyen TN, Zaidat OO, Gupta R, Nogueira RG, Tariq N, Kalia JS, Norbash AM, Qureshi AI. Balloon Angioplasty for Intracranial Atherosclerotic Disease: Periprocedural Risks and Short Term Outcomes in a Multicenter Study. Stroke 2011;42:107-111.
Watanabe M, Sakai O, Norbash AM, Jara H. Accurate brain volumetry with diffusion-weighted spin-echo single-shot echo-planar-imaging and dual-clustering segmentation: comparison with volumetry-validated quantitative magnetic resonance imaging.
Thiex R, Norbash AM, Frerichs KU. The safety of dedicated-team catheter-based diagnostic cerebral angiography in the era of advanced noninvasive imaging. Am J Neuroradiol 2010;31:230-4.
Nguyen TN, Chin LS, Souza R, Norbash AM. Transvenous embolization of a ruptured cerebral arteriovenous malformation with en-passage arterial supply: initial case report. J Neuroint Surg 2010.
Karakis I, Nguyen TN, Babikian VL, Norbash A. Balloon angioplasty of the anterior cerebral artery A2 segment for recurrent, symptomatic atherosclerotic disease. Journal of Neurosurgery 2010;112:582-4
Romero JR, Pikula A, Nguyen TN, Nien YL, Norbash A, Babikian VL. Cerebral Collateral Circulation in Carotid Artery Disease. Current Cardiology Reviews 2009;5(4):279-288.
Jara H, Sakai O, Mankal P, Irving RP, Norbash AM. Multispectral quantitative magnetic resonance imaging of brain iron stores: a theoretical perspective. Top Magn Reson Imaging. 2006;17(1):19-30.
Kacher DF, Frerichs K, Pettit J, Campbell PK, Meunch T, Norbash AM. DuraSeal magnetic resonance and computed tomography imaging: evaluation in a canine craniotomy model. Neurosurgery 2006;58(1 Suppl):ONS140-7.
Uchiyama Y, Abe T, Hirohata M, Tanaka N, Kojima K, Nishimura H, Norbash AM, Hayabuchi N. Blood brain-barrier disruption of nonionic iodinated contrast medium following coil embolization of a ruptured intracerebral aneurysm. AJNR 2004;25(10):1783-6.
Berlis A, Lutsep H, Barnwell S, Norbash A, Wechsler L, Jungreis CA, Woolfenden A, Redekop G, Hartmann M, Schumacher M. Mechanical thrombolysis in acute ischemic stroke with endovascular photoacoustic recanalization. Stroke 2004;35(5):1112-6.
Hirohata M, Abe T, Morimitsu H, Fujimura N, Shigemori M, Norbash AM. Preoperative selective internal carotid dural branch embolization for petroclival meningiomas. Neuroradiology 2003;45(9):656-60.
Abe T, Hirohata M, Tanaka N, Uchiyama Y, Kojima K, Fujimoto K, Norbash AM, Hayabuchi N. Clinical benefits of rotational 3D angiography in endovascular treatment of ruptured cerebral aneurysm. AJNR 2002;23(4):686-8.
Frerichs KF, Baker J, Norbash AM. Intra-arterial stroke thrombolysis and carotid stenting: methods for the treatment of ischemic cerebrovascular disease. Seminars in Roentgenology 2002;37(4):255-265.
Frerichs KU, Pergolizzi RS, Norbash AM. Treatment of carotid artery disease with angioplasty and stenting. In: Whittemore (ed.). Advances in Vascular Surgery, Volume 10. Philadelphia; Mosby, 2002:11-33.
Rordorf G, Bellon RJ, Budzik RE Jr, Farkas J, Reinking GF, Pergolizzi RS, Ezzeddine M, Norbash AM, Gonzalez RG, Putman CM. Silent thromboembolic events associated with the treatment of unruptured cerebral aneurysms by use of Guglielmi detachable coils: prospective study applying diffusion-weighted imaging. AJNR 2001;22(1):5-10.
Woolfenden AR, Tong DC, Norbash AM, Ali AO, Marks MP, O'Brien MW, Albers GW. Basilar artery stenosis: clinical and neuroradiographic features. J Stroke Cerebrovasc Dis 2000;9(2):57-63.
Norbash AM, Busick D, Marks MP. Techniques for reducing interventional neuroradiologic skin dose: tube position rotation and supplemental beam filtration.AJNR 1996;17(1):41-9.
Blankenberg FG, Norbash AM, Lane B, Stevenson DK, Bracci PM, Enzmann DR. Neonatal intracranial ischemia and hemorrhage: diagnosis with US, CT, and MR imaging. Radiology 1996;199(1):253-9.
Marks MP, Dake MD, Steinberg GK, Norbash AM, Lane B. Stent placement for arterial and venous cerebrovascular disease: Preliminary experience. Radiology 1994;191:441-446.
Norbash AM, Marks MP, Lane B. Correlation of pressure measurements and angiographic characteristics predisposing to hemorrhage and steal in cerebral AVMs. American Journal of Neuroradiology 1994;15:809-813.
Norbash AM, Pelc NJ, Shimakawa A, Enzmann DE. Shunt flow measurement and evaluation of valve oscillation with a spin-echo phase contrast MR Sequence. Radiology 1994; 190:560-564.
Norbash AM, Glover G, Enzmann DR. Intracerebral lesion contrast with spin-echo and fast spin-echo pulse sequences. Radiology 1992;185:661-665.