BMC Stroke Center offers contemporary treatment for brain, carotid and spinal vascular diseases.

Stroke & Cerebrovascular Center

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Services – Stroke Prevention & Treatment Center

Acute Stroke Protocol – tPA Guidelines for Acute Ischemic Stroke


t-PA Dosing Chart (estimated weight)


Estimated Weight (lbs) Conversion to Kilograms (Kg) Total iv t-PA Dose (mg)  at 0.9 mg/kg t-PA Bolus (mg) *10% of total* t-PA Bolus (ml) Discard Dose  t-PA (Not for infusion) Infusion Dose (mg) Infusion Rate (ml/hr)

220+

100.0

90.0

9.0

9.0

10.0

81.0

81.0

210

95.5

85.9

8.6

8.6

14.1

77.3

77.3

200

90.9

81.8

8.2

8.2

18.2

73.6

73.6

190

86.4

77.7

7.8

7.8

22.3

70.0

70.0

180

81.8

73.6

7.4

7.4

26.4

66.3

66.3

170

77.3

69.5

7.0

7.0

30.5

62.6

62.6

160

72.7

65.5

6.5

6.5

34.5

58.9

58.9

150

68.2

61.4

6.1

6.1

38.6

55.2

55.2

140

63.6

57.3

5.7

5.7

42.7

51.5

51.5

130

59.1

53.2

5.3

5.3

46.8

47.9

47.9

120

54.5

49.1

4.9

4.9

50.9

44.2

44.2

110

50.0

45.0

4.5

4.5

55.0

40.5

40.5

100

45.5

40.9

4.1

4.1

59.1

36.8

36.8

Appointments

Call: 617.638.8456
Fax: 617.638.8465
Email: stroke@bmc.org


Boston Medical Center
Department of Neurology
Shapiro Center
7th Floor, Suite 7B
725 Albany Street
Boston, MA 02118


Refer a Patient

Call: 800.682.2862


For Research Information

Contact Helena Lau,
Call: 617.414.1171
Fax: 617.638.5354
stroke@bmc.org or
hlau@bu.edu


Learn More

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Areas of Expertise

Arteriovenous Malformations (AVMs)
Brain Aneurysm Care
Carotid Artery Disease
Dural Arteriovenous Fistula (DAVF)
Spine Care
Stroke Prevention & Treatment

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