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Department of Orthopaedic Surgery


Thomas A. Einhorn, M.D. Publications

Scientific Articles
Gerstenfeld, L. C., Thiede, M., Seibert, K., Mielke, C., Phippard, D., Svagr, B., Cullinane, D. and Einhorn, T. A.: Differential Inhibition of Fracture Healing by Non-Selective and Cyclooxygenase-2 Selective Non-Steroidal Anti-Inflammatory Drugs. J. ORTHOP. RES. 21:670-675, 2003.

Bhattacharyya, T., Tornetta, P., Healy, W. L., and Einhorn, T. A.: The Validity of Supporting Data for Claims Made in Orthopaedic Print Advertisements. J. BONE JOINT SURG. 85A:1224-1228, 2003.

Einhorn, T. A., Majeska, R. J., Mohaideen, A., Kagel, E. M., Bouxsein, M. L., Turek, T. J. and Wozney, J. M.: A Single Percutaneous Injection of Recombinant Human Bone Morphogenetic Protein-2 Accelerates Fracture Repair. J. BONE JOINT SURG. 85A:1425-1435, 2003.

Einhorn, T. A.: Clinical Applications of Recombinant Human BMPs: Early Experience and Future Development. J. BONE JOINT SURG. 85A(Suppl. 3):82-88, 2003.

Gerstenfeld, L.C., Cho, T-J., Kon, T., Aizawa, T., Tsay, A., Barnes, G. L., Graves, D. T., and Einhorn, T. A.: Impaired Fracture Healing in the Absence of Tumor Necrosis Factor-Ą Signaling: The Role of TNF-a in Endochondral Cartilage Resorption. J. BONE MINER. RES., 18:1584-1592, 2003.

Shea, C. M., Edgar, C. M., Einhorn, T. A., and Gerstenfeld, L. C.: BMP Treatment of C3H10T1/2 Mesenchymal Stem Cells Induces Both Chondrogenesis and Osteogenesis. J. CELL BIOCHEM, 15:1112-1127, 2003.

Pacicca, D. M., Patel, N., Lee, C., Salisbury, K., Lehman, W., Carvalho, R., Gerstenfeld, L.C., and Einhorn, T. A.: Expression of Angiogenic Factors during Distraction Osteogenesis. BONE, 33:889-898, 2003.

Schmidmaier, G., Wildemann, B., Melis, B., Krummrey, G., Einhorn, T. A., Haas, N. P. And Raschke, M.: Development and Characterization of a Standard Closed Tibial Fracture Model in the Rat. EUR. J. TRAUMA, 30:35-42, 2004.

Gerstenfeld, L. C. and Einhorn, T. A.: COX Inhibitors and Their Effects on Bone Healing. EXPERT OPIN. DRUG SAF., 2:131-136, 2004.

Nakazawa, T., Nakajima, A., Seki, N., Okawa, A., Kato, M., Moriya, H., Amizuka, N., Einhorn, T.A. and Yamazaki, M.: Gene Expression of Periostin in the Early Stage of Fracture Healing Detected by cDNA Microarray Analysis. J. ORTHOP. RES., 22:520-525, 2004.

Carvalho, R. S., Einhorn, T. A., Lehman, W., Edgar, C., Alyamani, A., Apazidis, A., Pacicca, D., Clemens, T. L., and Gerstenfeld, L. C.: The Role of Angiogenesis in a Murine Model of Distraction Osteogenesis. BONE 34:849-861, 2004.

Barnes, G. L., Hebert, K., Kamal, M., Javed, A., Einhorn, T. A., Lian, J.B., Stein, G. S., and Gerstenfeld, L. C.: Fidelity of Runx2 Activity in Breast Cancer Cells is Required for the Generation of Metastases Associated Osteolytic Disease. CANCER RES., 64:4506-4513, 2004.

Bhandari, M., Swiontkowski, M., Einhorn, T. A., Tornetta III, P., Schemitsch, E., and Wright, J., G.: Inter-observer Agreement in the Application of the Levels of Evidence to Scientific Papers in The Journal of Bone and Joint Surgery. J. BONE JOINT SURG., 86A:1717-1720, 2004.

Lochner, H. V. and Einhorn, T. A. : Advances in Therapeutic Diagnostics: Hormone Replacement Therapy. J. AMER. ACAD. ORTHOP. SURG., 12:291-294, 2004.

Kim, H. J. W., Bian, H., Randall, T., Garces, A., Gerstenfeld, L. C., and Einhorn, T. A.: Increased VEGF Expression in the Epiphyseal Cartilage Following Ischemic Necrosis of the Capital Femoral Epiphysis. J. BONE MINER. RES., 19:2041-2048, 2004.

Lehmann, W., Schinke, T., Catala-Lehnen, P., Gebauer, M., Pogoda, P., Gerstenfeld, L.C., Rueger, J.M., Einhorn, T. A., and Amling, M.: Absence of Mouse Pleiotrophin Does Not Affect Bone Formation In Vivo. BONE, 35:1247-1255, 2004.

Mont, M. A., Ragland, P. S., Biggins, B., Friedlaender, G., Patel, T., Cook, S., Etienne, G., Shimmin, A., Kildey, R., Rueger, D.C., and Einhorn, T. A.: Use of Bone Morphogenetic Proteins for Musculoskeletal Applications: An Overview. J. BONE JOINT SURG., 86A:S2:41-55, 2004.

Bhandari, M., Bajammal, S., Guyatt, G. H., Griffith, L., Busse, J., W., Schunermann, H., and Einhorn, T., A.:The Effect of Bisphosphonates on Periprosthetic Bone Mineral Density After Total Joint Arthroplasty. A Meta-Analysis. J. BONE JOINT SURG., 87A:293-301, 2005.

Lehmann, W., Edgar, C. M., Wang, K., Cho, T-J., Barnes, G. L., Kakar, S., Graves, D. T., Rueger, J. M., Gerstenfeld, L. C., and Einhorn, T. A.: Tumor Necrosis Factor Alpha (TNF-Ą) Coordinately Regulates the Expression of Specific Matrix Metalloproteinases (MMPs) and Angiogenic Factors During Fracture Healing. BONE, 36:300-310, 2005.


Textbooks
Orthopaedic Basic Science: The Biology and Biomechanics of the Musculoskeletal System. 2nd Edition. J.A. Buckwalter, T.A. Einhorn, and S.R. Simon, Eds., Rosemont, Illinois, AM. ACAD. ORTHOP. SURG., 2000.

Orthopaedic Surgery Essentials: P. Tornetta, III and T. A. Einhorn, Series Eds., Philadelphia, PA., LIPPINCOTT WILLIAMS & WILKINS, 2003.

Bone Tissue Engineering: J. O. Hollinger, T. A. Einhorn, B. Doll and C. Sfeir Eds., Boca Raton, Fla. CRC Press, 2004.








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