1. Describe the classification of infertility (ie, primary versus secondary). 2. List the principal causes of primary and secondary infertility. 3. Elicit a pertinent history to determine the most likely cause of infertility. 4. Perform a focused physical examination to determine the most likely cause of infertility. 5. Perform selected diagnostic tests to determine the most likely cause of infertility, such as:
a. Review of basal body temperature chart b. Endometrial biopsy c. Hysterosalpingography d. Laparoscopy e. Microbiologic cultures of the lower and upper genital tract
a. Endometrial histology b. Semen analysis and culture c. Sperm antibody test d. Urine ovulation indicator e. Blood assays
a. Clomiphene citrate b. Prednisone c. Insulin-sensitivity agents such as metformin
a. Lysis of pelvic adhesions b. Excision of endometriomas c. Fulguration of endometriotic implants
a. In vitro fertilization (IVF) b. Gamete intrafallopian transfer (GIFT) c. Zygote intrafallopian transfer (ZIFT) d. Intracytoplasmic sperm injection (ICSI) e. Gamete donation f. Preimplantation genetic diagnosis
a. Hymenal abnormalities, such as imperforate hymen b. Vaginal agenesis c. Vaginal septum
(1) Obstructive and non obstructive (2) Longitudinal and transverse
d. Uterine septum e. Unicornuate or bicornuate uterus f. Uterine didelphys g. Uterine horn
a. Ulrasonography b. Endocrinologic assays c. Peripheral blood karyotype assessments d. CT/MRI scan
a. Pedigree analysis b. Detection of underlying medical disorders c. Exposure to toxins
a. Genital tract malformations b. Galactorrhea c. Hypothyroidism d. Autoimmune disease
a. Microbiologic cultures of the genital tract b. Hysteroscopy c. Endometrial biopsy
a. Serum prolactin b. Thyroid function tests c. Serum progesterone d. Serologic tests for connective tissue disease e. Peripheral blood karyotype f. Hysterosalpingography
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