BMC | Obstetrics and Gynecology Residency Program

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GYN PGY3/PGY4
Therapies

1. Describe the general mechanism of action of chemotherapy.
2. Describe the indications for chemotherapy in the treatment of gynecologic neoplasms.
3. Describe the likelihood of response of each common gynecologic malignancy to chemotherapeutic agents.
4. Describe the mechanisms of action and most appropriate indication for chemotherapeutic agents, such as:

a. Alkylating agents
b. Antimetabolites
c. Vinca alkaloids
d. Antibiotics
e. Hormones
f. Heavy metals
g. Immunotherapy

1. Describe the general principles of radiation therapy.
2. Describe the indications for radiation therapy in the treatment of gynecologic neoplasms.
3. Describe the mechanism of action of:

a. Intracavitary irradiation
b. External-beam irradiation
c. Interstitial irradiation
d. Radioisotopes
e. Palliative radiation therapy

a. Classification and FIGO staging of disease and histology
b. Age of patient
c. Underlying medical conditions
d. Implications for future fertility
e. Concomitant therapy with radiosensitizers or chemotherapy
f. Previous abdominal procedures
g. Maximal dose tolerance of selected organ systems

1. Describe the basic principles of palliative care.
2. Describe medical, radiation, and operative modalities for palliation of symptoms in terminally ill patients.
3. Describe the appropriate indications for a do-not-resuscitate (DNR) order.
4. Describe the medical, ethical, and legal implications of such an order.
5. Describe the concept of therapeutic index when considering medical or operative intervention to improve patients’ quality of life.
6. Describe the basic principles of pain management.

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