Center for Minimally Invasive Esophageal Therapies

Text Size Increase Text Size Decrease Font Size Print Page

Diseases & Conditions

High-Grade Dysplasia

At Boston Medical Center we pride ourselves on our ability to diagnose and treat esophageal disorders, including high-grade dysplasia of the esophagus, using the most advanced therapies. We do so in a caring and compassionate enviornment, where our priority is the well-being of you and your family.

What is High-Grade Dysplasia of the Esophagus?

High grade dysplasia (HGD) refers to precancerous changes in the cells of the esophagus. Gastroesophageal reflux disease (GERD) can be complicated by Barrett’s esophagus (BE), a change in the normal esophageal cells to intestinal-like cells. BE cells can become abnormal or dysplastic. Low grade and then high grade dysplasia can develop. HGD significantly increases a person’s risk for esophageal adenocarcinoma and in most cases will progress to cancer without any treatment. When someone is diagnosed with HGD, an intervention is advised including endoscopic resection and Barrx ablation or in some cases an esophagectomy is recommended for treatment.  

Diagnostic Procedures

What are the Symptoms of High-Grade Dysplasia?

You may not experience any symptoms, but they can include:

What are the Causes?

Dysplasia is a complication of gastroesophageal disease (GERD) and BE.

How is High-Grade Dysplasia Diagnosed?

Diagnosis is often difficult, as symptoms may be limited. 

How is High-Grade Dysplasia Treated?

There are a variety of ways we can treat your high-grade dysplasia. Your physician will work with you and your family to decide the most appropriate course of action. Your options include:

Diseases & Conditions
Other Treatments
Our Team
Patient Information


Call: 617.638.5600
Fax: 617.638.7382

Boston Medical Center
Center for Minimally Invasive Esophageal Therapies
Moakley Building
3rd Floor,
830 Harrison Avenue
Boston, MA 02118

Refer a Patient

Call: 617.638.5600
Fax: 617.638.7382

Administrative Office

Boston Medical Center
88 East Newton Street, Suite 402
Boston, MA 02118
Call: 617.638.5600
Fax: 617.638.7382

Learn More

Quick Links

Cancer Center
Center for Digestive Disorders
Center for Thoracic Oncology
Medical Oncology
Radiation Oncology
Thoracic Surgery

Directions to BMC
BMC Campus Virtual Tour

Downloads (PDF)

BMC Campus Map
What Makes BMC Special